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Richard F Kefford Selected Research

L-Lactate Dehydrogenase (Lactate Dehydrogenase)

3/2016Overall Survival and Durable Responses in Patients With BRAF V600-Mutant Metastatic Melanoma Receiving Dabrafenib Combined With Trametinib.
3/2010A randomized, double-blind, placebo-controlled study of high-dose bosentan in patients with stage IV metastatic melanoma receiving first-line dacarbazine chemotherapy.

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Richard F Kefford Research Topics

Disease

98Melanoma (Melanoma, Malignant)
01/2021 - 03/2003
45Neoplasms (Cancer)
11/2020 - 02/2003
13Neoplasm Metastasis (Metastasis)
11/2018 - 07/2012
10Disease Progression
12/2015 - 06/2007
6Brain Neoplasms (Brain Tumor)
01/2021 - 05/2012
3Nevus (Nevi)
11/2011 - 08/2009
3Pancreatic Neoplasms (Pancreatic Cancer)
07/2007 - 10/2006
2Uveal melanoma
11/2018 - 10/2006
2Fever (Fevers)
10/2014 - 11/2012
2Nervous System Neoplasms (Neoplasms, Nervous System)
07/2007 - 12/2006
1Monosomy
11/2018
1Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)
04/2016
1Hemolysis
04/2016
1Adenocarcinoma
04/2015
1Tenosynovitis
01/2015
1Arthritis (Polyarthritis)
01/2015
1Sarcoma (Soft Tissue Sarcoma)
10/2014
1Keratosis
10/2014
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
10/2014
1Acneiform Eruptions
10/2014
1Facial Paralysis (Facial Palsy)
04/2013
1Carcinogenesis
12/2012
1Neutropenia
11/2012

Drug/Important Bio-Agent (IBA)

22dabrafenibIBA
01/2019 - 03/2012
16Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
10/2017 - 07/2012
13trametinibIBA
01/2020 - 11/2012
10Pharmaceutical PreparationsIBA
01/2015 - 05/2012
9Biomarkers (Surrogate Marker)IBA
01/2020 - 05/2012
9VemurafenibIBA
12/2015 - 03/2012
9Tumor Suppressor Protein p14ARF (p14ARF)IBA
02/2010 - 02/2003
8Immune Checkpoint InhibitorsIBA
01/2020 - 08/2015
8Proteins (Proteins, Gene)FDA Link
01/2018 - 02/2009
7DNA (Deoxyribonucleic Acid)IBA
08/2020 - 03/2003
6Phosphotransferases (Kinase)IBA
01/2020 - 12/2014
6Cyclin-Dependent Kinase Inhibitor p16IBA
11/2011 - 10/2008
5Circulating Tumor DNAIBA
08/2020 - 01/2018
5Mitogen-Activated Protein KinasesIBA
01/2020 - 07/2013
5AntibodiesIBA
01/2018 - 07/2012
3ParaffinIBA
01/2019 - 01/2013
3Formaldehyde (Formol)FDA Link
01/2019 - 01/2013
3NivolumabIBA
09/2017 - 04/2016
3pembrolizumabIBA
09/2017 - 01/2015
3Type 1 Melanocortin ReceptorIBA
09/2013 - 03/2003
2Cell-Free Nucleic AcidsIBA
08/2020 - 09/2013
2RNA (Ribonucleic Acid)IBA
01/2020 - 01/2018
2CytokinesIBA
01/2019 - 03/2014
2IpilimumabIBA
01/2018 - 04/2016
2InterferonsIBA
01/2018 - 03/2017
2CateninsIBA
10/2017 - 01/2014
2L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
03/2016 - 03/2010
2Biological ProductsIBA
12/2015 - 03/2009
2Cyclin-Dependent Kinases (cdk Proteins)IBA
03/2013 - 11/2005
2Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
08/2009 - 07/2007
1Histocompatibility Antigens Class IIBA
11/2020
1AntigensIBA
11/2020
1Immune Checkpoint ProteinsIBA
01/2020
1Dual Specificity Phosphatase 6IBA
01/2019
1Peptide Initiation Factors (Initiation Factor)IBA
11/2018
1RNA Splicing FactorsIBA
11/2018
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
11/2018
1Programmed Cell Death 1 ReceptorIBA
01/2018
1Tumor Biomarkers (Tumor Markers)IBA
01/2018
1encorafenibIBA
09/2017
1Blood Proteins (Serum Proteins)IBA
01/2017
1Monoclonal AntibodiesIBA
04/2016
1IsoantibodiesIBA
04/2016
1tributyl phosphate (TBP)IBA
10/2014
1Adrenal Cortex Hormones (Corticosteroids)IBA
10/2014
1Acetaminophen (Paracetamol)FDA LinkGeneric
10/2014
1SteroidsIBA
10/2014
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
10/2014
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
09/2014
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
03/2014
1ChemokinesIBA
03/2014
1Proto-Oncogene Proteins c-kit (Proto-Oncogene Protein c-kit)IBA
07/2013
1Imatinib Mesylate (Gleevec)FDA Link
07/2013
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
07/2013
1nilotinibFDA Link
07/2013
1Cadherins (E-Cadherin)IBA
05/2013
1A-Form DNA (A-DNA)IBA
03/2013
1thiamine triphosphorate (TTP)IBA
01/2013
1AmylasesFDA Link
11/2012
1Lipase (Acid Lipase)FDA Link
11/2012
1Proto-Oncogene Proteins B-rafIBA
07/2012
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
03/2012
1Granzymes (Granzyme)IBA
03/2012
1PLX 4720IBA
03/2012
1Microphthalmia-Associated Transcription FactorIBA
11/2011
1CI 22IBA
04/2011
1Endothelin Receptor AntagonistsIBA
03/2010
1Dacarbazine (DIC)FDA LinkGeneric
03/2010
1Endothelins (Endothelin)IBA
03/2010

Therapy/Procedure

33Therapeutics
01/2021 - 02/2005
9Immunotherapy
11/2020 - 03/2010
4Drug Therapy (Chemotherapy)
01/2021 - 06/2007
2Aftercare (After-Treatment)
10/2014 - 03/2012
1Radiotherapy
01/2021
1Neoadjuvant Therapy
01/2019
1Drug Tapering
10/2014
1Precision Medicine
12/2012